What clinical manifestations are expected in a patient with hypothyroidism? Select all that apply.

In patients with hypothyroidism, clinical manifestations can vary widely, but some of the most common symptoms include cognitive impairments such as forgetfulness, fatigue, and weakness.

Forgetfulness is linked to the overall slowdown of metabolic processes in the body due to reduced levels of thyroid hormones, which are essential for brain function. This hormone deficiency can affect mood and cognitive clarity, leading to difficulties with memory and concentration.

Fatigue and weakness are also hallmark symptoms of hypothyroidism. As the metabolism slows down, patients often report a lack of energy and an overall sense of lethargy. The muscles may feel weak, and the endurance for physical activities tends to decline, which are direct consequences of insufficient thyroid hormone levels affecting cellular energy production.

Insomnia is typically not a primary symptom of hypothyroidism; rather, in many cases, patients may experience excessive daytime sleepiness and disruptions in sleep patterns due to fatigue. Likewise, hyperactivity is contrary to what would be expected in hypothyroidism, as it usually leads to a decreased level of physical activity and energy.

Thus, forgetfulness and fatigue and weakness aptly capture the symptoms that are representative of hypothyroidism.