What is the first step in the dexamethasone suppression test?

The first step in the dexamethasone suppression test is to hold medications that may affect the test. This is crucial because the purpose of the test is to assess how the body regulates cortisol production in response to dexamethasone administration. If a patient continues to take medications that influence cortisol levels, such as certain steroids or other corticosteroids, it can confound the results and lead to inaccurate conclusions about adrenal function or potential disorders such as Cushing's syndrome. Therefore, ensuring that any interfering substances are held prior to the test allows for a clear interpretation of how the body responds to dexamethasone, establishing a reliable baseline for cortisol levels during the assessment.